Laser-assisted drug delivery, or LADD, refers to the delivery of a drug via channels created by lasers or radiofrequency microneedling. At Lumine Dermatology & Laser Clinic, this can be via fractional ablative laser (CO2), fractional non-ablative laser (MOXI), or radiofrequency microneedling (Sylfirm X).
Post-procedure, direct application of therapeutic agents like triamcinolone, poly-L-lactic acid (PLLA), exosomes and tranexamic acid can help enhance the results of the treatment procedure. This method can be finely tuned to suit the specific treatment area, ensuring the medication is delivered exactly where needed, maximising efficacy while minimising the need for injections.
The skin protects us from external influences such as harmful microorganisms (bacteria, viruses), UV rays, and mechanical damage. While the absorption of topical products through the skin is effective, the skin’s barrier function still significantly hinders the absorption of certain substances. Laser-assisted drug delivery works by overcoming this barrier.
The process starts with the laser targeting the treatment area to create microchannels. These microscopic openings allow topically applied medications to bypass the skin's natural barrier and penetrate the deeper layers of the skin, increasing its effectiveness.
This direct access means that delivery of the laser-assisted topicals works more efficiently, offering improved results compared to traditional topical applications. The precision of this technique also reduces the risk of topical medication affecting surrounding unaffected areas, keeping the focus strictly on the problem spots.
Not all microchannels created by various devices are the same. Generally, the size and duration of the channels are greatest for CO2 lasers, followed by the MOXI laser, and then radiofrequency microneedling. An experienced dermatologist in this technique can advise you accordingly on which device to use and which drug is suitable for topical delivery.
Laser-assisted drug delivery is effective in treating the following skin conditions:
The number of LADD sessions needed can vary widely depending on the patient's goals and the severity of the condition. Some may see satisfactory results after just one or two treatments, while others might require several sessions. Typically, these sessions are spaced out to allow the skin to recover properly between treatments, with the exact timing depending on the individual's response to the procedure.
To sustain the results over time, maintenance treatments may be recommended after completing the initial series of laser-assisted drug delivery sessions. These maintenance sessions are typically spaced several months apart, depending on individual needs and response to treatment.
If you are interested in laser-assisted drug delivery, contact us today to book a skin consultation.
Can laser-assisted drug delivery be used on all skin types?
Yes, but adjustments may be needed for darker skin tones to minimise pigmentation risks. Consultation with an experienced dermatologist is essential.
What are the potential side effects of laser-assisted drug delivery?
Temporary redness, swelling, and mild discomfort are common. Rarely, pigmentation changes, infection, or scarring may occur.
How should I prepare for a laser-assisted drug delivery session?
To prepare for this treatment, stop using retinol creams and limit sun exposure to the treatment area before the procedure. Recovery involves minor discomfort and redness for a few days, with specific post-care instructions provided by your dermatologist to support healing. For more information, contact your dermatologist.
Can laser-assisted drug delivery be combined with other treatments?
Yes, it can be combined with other treatments under a dermatologist's guidance for enhanced results.
