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Skin Cancer Surgery

What conditions can skin cancer surgery treat?

Skin cancer surgery can help treat the following conditions:

  • Basal cell carcinoma (BCC): BCC is the most common type of skin cancer, which can be successfully treated with various surgical methods.
  • Squamous cell carcinoma (SCC): SCC is a common skin cancer characterised by scaly red patches or a thick scaly nodule. It can be treated through surgical removal to prevent its spread.
  • Melanoma: melanoma is an aggressive form of skin cancer originating in pigment-producing cells (melanocytes).

What is skin cancer surgery?

There are various types of skin cancer surgeries, and the common approaches are as follows:

(i) Mohs micrographic surgery

Mohs micrographic surgery is a precise and specialised technique primarily used to treat specific types of skin cancer, such as basal cell carcinomas (BCC) and squamous cell carcinomas (SCC). This staged procedure involves meticulously removing thin layers of cancerous tissue one by one and promptly examining them under a microscope until no cancer cells remain.

It has good cure rates for non-melanoma skin cancers like BCCs and SCCs. Mohs surgery also prioritises the maximum preservation of healthy tissue, resulting in minimal scarring and favourable cosmetic outcomes. It is the ideal surgery for skin cancers at cosmetically sensitive sites, recurrent skin cancers, and aggressive skin tumours with indistinct margins.

What are the steps of  Mohs micrographic surgery?

This surgery involves removing skin cancer in stages under local anaesthesia. After each layer, the tissue removed is examined under the microscope until we reach healthy, cancer-free tissue in the margins.

At Lumine Dermatology & Laser Clinic, this procedure is carried out by a dermatologist with subspecialty training in Mohs surgery. The surgeon removes the skin cancer and examines the surgical margins under a microscope.

  • Step 1: a thin (typically 1-2 mm) cuff of tissue is removed around the visible tumour. During the excision, measures are taken to ensure the orientation of the specimen is maintained.
  • Step 2: the removed tissue is then colour-coded with tissue dyes. A mapping process is in place so that any residual tumour identified on the microscope can be more precisely mapped to the patient’s actual skin defect.
  • Step 3: a specialised technician processes the tissue on the spot to create horizontal sections of the entire excision margin.
  • Step 4: the Mohs surgeon examines the microscopic sections for any residual tumour. The special sectioning method in Mohs surgery allows for a more complete visualisation of the skin cancer under the microscope, so any residual tumour is more likely to be identified and can be mapped precisely.
  • Step 5: a second layer is taken per steps 1-4. The process repeats until no tumour is visualised at the margins.
  • Step 6: the Mohs surgery is complete, and the surgeon can reconstruct the defect.
(ii) Wide local excision

Wide local excision involves removing the entire cancerous area and a 3-10 mm margin of tissue surrounding it. It is used for BCC, SCC, and early-stage melanomas. After the surgery, the wound is closed with stitches. Wide local excision continues to be a viable treatment choice for skin cancers deemed lower in risk, particularly those in less aesthetically sensitive regions like the trunk and limbs.

Additionally, it is advantageous for certain skin cancers characterised by unpredictable growth patterns, such as melanoma and extramammary Paget’s disease.

What are the steps of wide local excision?

  • Step 1: the targeted area and a margin of perceivably healthy surrounding skin are marked out. The amount of healthy skin removed depends on the tumour's size, subtype, and depth.
  • Step 2: once the tumour and surrounding skin have been removed, the wound is closed with sutures. If the opening is large, skin grafts or flaps may be used to close the wound.
  • Step 3: the surgical margins will be sent to the lab for analysis to ensure that all traces of cancer have been removed. If cancer is still detected in the area, additional surgery may be required.

In contrast to the horizontal sectioning method employed in Mohs surgery, wide local excisions utilise a "bread loaf" technique to section excised tissues. The margins assessed with this technique are typically smaller than those observed in Mohs surgery. This variance may contribute to the increased recurrence risk associated with wide local excisions, particularly for high-risk skin cancers.

(iii) Curettage and cautery (C&C)

Curettage and cautery can be employed for premalignant skin cancers or superficial basal cell carcinomas. The skin lesion is scraped off, and the base of the lesion is cauterised to remove any remnant abnormal cells.

This technique is less precise but may be suitable in select cases.

What is the difference between Mohs Micrographic Surgery and Wide Local Excision?

Mohs Micrographic SurgeryWide Local Excision
Preferred for non-melanoma skin cancers like BCC and SCC, with good cure rates compared to wide local excisionTypically chosen for tumours with irregular growth patterns such as melanoma or extramammary Paget's disease
More thorough examination of both peripheral and deep surgical margins for comprehensive cancer removalLess thorough examination of peripheral and deep margins due to “bread-loafing” technique
Allows for maximal preservation of healthy tissue during tumour removalLess tissue-sparing than Mohs Micrographic Surgery
Entire process, from tumour removal to microscopic examination and reconstruction, is completed on the same dayDelay between surgical excision and histology results, with the possibility of additional procedures if margins are found to be positive for cancer
Takes longer to complete and is done in stagesQuick to perform and in one sitting
Requires specialised skills and more tediousLess tedious
More expensiveLess costly

Frequently asked questions

How long does it take to recover from skin cancer surgery?

Recovery time varies depending on the type of surgery performed, the location and size of the tumour, and your overall health.

For minor surgeries involving small, non-melanoma skin cancers, recovery will take 1-2 weeks. The wound care will be relatively straightforward, involving keeping the area clean and protected while it heals. Most patients can resume normal activities within a few days to weeks, with complete healing typically occurring within a few months.

For more extensive surgeries involving larger or more aggressive tumours, the recovery period can be longer, i.e., a few weeks to two months.

After skin cancer surgery, you must protect your skin from the sun and conduct regular self-examination. We will need to see you every few months post-surgery to monitor the scar for recurrence and for any new skin cancers. We may prescribe supplements to help minimise the risk of forming new skin cancers.

Will I have visible scars after skin cancer surgery?

This is a valid concern for our patients undergoing skin cancer surgery; at Lumine Dermatology & Laser Clinic, we reassure you that we will do our best to reduce your downtime and minimise scarring as much as possible.

One way to minimise scarring is to use techniques like Mohs surgery, which prioritises aesthetic outcomes by maximising tissue preservation. Following your dermatologist’s wound care instructions carefully, avoiding sun exposure to the healing area, and applying scar gels can help minimise the appearance of post-surgical scars.

If scarring is a concern, treatments available can help improve the appearance of scars, including laser therapy, microneedling radiofrequency, polynucleotide injections and, in some cases, surgical revision. These options can be discussed in detail during your follow-up appointments.

Are there alternative treatments to skin cancer surgery?

Depending on the type and stage of skin cancer, alternative treatments such as radiation therapy or topical medications may be considered. However, surgery remains a primary and effective option for many cases.

When is Mohs micrographic surgery appropriate?

  • Tumours with indistinct borders
  • Large tumours of the head and neck
  • High-risk subtypes of BCC/SCC, e.g. infiltrative, morphoeic, poorly differentiated
  • Recurrent or incompletely excised tumours
  • Tumour developing from the previous site of radiotherapy
  • Tumour emerging at sites necessitating maximal tissue preservation is imperative, e.g. eyes, nose, ears, lips, fingers

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1 Scotts Road #04-15/16 Shaw Centre Singapore 228208





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