Skin ageing is an inevitable process, but with the advancements in dermatological treatments, it is now possible to slow down the loss of collagen and restore a youthful, radiant appearance. One of the most advanced injectable skin boosters available today is Poly-D, L lactic acid (PDLLA) and hyaluronic acid (HA), a hybrid collagen-stimulating skin booster e.g Juvelook.
If you’re looking for a non-surgical solution to improve skin texture, hydration, and elasticity while promoting natural collagen production, PDLLA and HA hybrid skin boosters (e.g Juvelook) may be the perfect choice for you. This guide will provide a detailed breakdown of everything you need to know about PDLLA and HA hybrid Skin Booster, its cost in Singapore, and the treatment process.
Poly-D, L lactic acid (PDLLA) is a biocompatible and biodegradable compound that has revolutionised the field of skin rejuvenation. PDLLA-based treatments, such as Juvelook, and Lenisna also known as Juvelook Volume, work by gradually stimulating collagen production, helping to restore skin firmness, elasticity, and hydration over time.
This biocompatible treatment is ideal for individuals looking to reduce wrinkles and fine lines, tighten skin, minimise pores, and remodel scars without undergoing invasive procedures.
Unlike traditional hyaluronic acid (HA) fillers, which mainly provide temporary volumisation and hydration, PDLLA-based skin boosters work deeper within the skin. They create long-lasting structural improvements by stimulating the skin’s natural ability to produce collagen and elastin.
PDLLA-HA hybrid skin booster e.g Juvelook is an advanced skin rejuvenation treatment designed to improve skin texture, hydration, and firmness. Derived from Poly-D, L lactic acid (PDLLA) and hyaluronic acid (HA), PDLLA-HA hybrid skin boosters stimulate natural collagen production while providing immediate skin hydration. Juvelook is a hybrid injectable that combines the biostimulatory properties of PDLLA with the hydrating benefits of HA, resulting in long-term skin rejuvenation.
What is novel about this cutting-edge aesthetic treatment is that it delivers both immediate and long-term results. The hyaluronic acid component instantly hydrates the skin, giving it a radiant and plump appearance. Meanwhile, PDLLA works over time to stimulate collagen production, improving skin elasticity, reducing fine lines, and tightening the skin.
PDLLA (e.g Juvelook Volume or Lenisna) can be injected deeper in the skin to stimulate collagen and result in sligh volumization. This usually involves a formulation with a higher concentration of PDLLA designed to provide mild volumisation along with collagen stimulation. It’s ideal for addressing deeper wrinkles, skin laxity, and volume loss in areas like the cheeks and temples.
Juvelook is an advanced skin rejuvenation treatment designed to improve skin texture, hydration, and firmness. Derived from Poly-D, L lactic acid (PDLLA) and hyaluronic acid (HA), Juvelook stimulates natural collagen production while providing immediate skin hydration. Juvelook is a hybrid injectable that combines the biostimulatory properties of PDLLA with the hydrating benefits of HA, resulting in long-term skin rejuvenation.
Juvelook skin booster is a cutting-edge aesthetic treatment that delivers both immediate and long-term results. The hyaluronic acid component instantly hydrates the skin, giving it a radiant and plump appearance. Meanwhile, PDLLA works over time to stimulate collagen production, improving skin elasticity, reducing fine lines, and tightening the skin.
Juvelook Volume, also known as Lenisna, is a formulation with a higher concentration of PDLLA designed to provide mild volumisation along with collagen stimulation. It’s ideal for addressing deeper wrinkles, skin laxity, and volume loss in areas like the cheeks and temples.
Traditional HA-based skin boosters mainly improve hydration and plumpness, but their effects typically last 9 to 12 months before requiring maintenance. PDLLA, on the other hand:
✔️ Stimulates collagen synthesis over time, leading to progressive skin improvement
✔️ Provides longer-lasting results – up to 2 years compared to 9- 12 months for HA-based fillers
✔️ Improves skin laxity, wrinkles, and fine lines without excessive volume
✔️ Can be used to treat acne scars and atrophic scars, making it a versatile treatment
PDLLA-based injectables, for example Juvelook and Lenisna (Juvelook Volume), offer a gradual, natural skin rejuvenation process, making them ideal for those seeking long-term anti-ageing solutions.
Hybrid HA-PDLLA e.g Juvelook does not just fill the skin with moisture—it actively stimulates collagen production over time, providing long-lasting skin improvement. The treatment works in two distinct phases:
When injected, the hyaluronic acid (HA) content instantly hydrates the skin, making it look plumper, more radiant, and refreshed. This immediate effect is similar to traditional HA skin boosters, giving an instant glow and volume boost.
Over the next 3 to 4 weeks, the PDLLA microparticles begin their work by triggering a controlled inflammatory response that activates fibroblasts—the skin’s natural collagen-producing cells.
The two primary mechanisms of collagen stimulation are:
✔️ Activation of Fibroblasts – The presence of PDLLA upregulates fibroblast activity, leading to the production of Type I collagen, which is essential for firm, youthful skin.
✔️ Regulation of Matrix Metalloproteinases (MMPs) – MMPs are enzymes that naturally break down collagen. PDLLA regulates these enzymes to prevent excessive collagen loss and maintain skin integrity.
This results in:
✔️ Tighter, firmer skin with reduced sagging
✔️ Smaller, refined pores
✔️ Smoother skin texture with fewer fine lines and wrinkles
✔️ Improved skin elasticity and hydration
The full results of PDLLA-HA hybrid skin boosters e.g Juvelook become visible after 3 to 6 months, and the collagen stimulation continues for up to 24 months.
PDLLA-HA hybrid skin boosters, e.g Juvelook, are suitable for a wide range of skin concerns, making it one of the most versatile injectable skin boosters available.
🔹 Skin Rejuvenation & Collagen Banking
If you have fine lines, wrinkles, or dull skin, Juvelook is an excellent option for preventing premature ageing and maintaining collagen levels in the skin.
🔹 Skin Tightening & Firming
For individuals who are concerned about mild skin laxity, Juvelook can firm and lift sagging skin without excessive volume, making it ideal for natural-looking rejuvenation.
🔹 Undereye Rejuvenation
Juvelook can smooth undereye hollows and reduce fine lines, making it a safer alternative to traditional tear-trough fillers.
🔹 Scar Remodeling & Acne Scar Treatment
Juvelook is highly effective for treating atrophic acne scars and post-traumatic scars by stimulating collagen regrowth. It can be injected directly into the scars or combined with subcision for enhanced scar remodelling.
Before undergoing PDLLA-HA treatment, a thorough consultation with a dermatologist is required to assess your skin condition and aesthetic goals.
Who should avoid PDLLA-HA (e.g Juvelook) treatment?
❌ Individuals with active acne, eczema, or rosacea
❌ Patients with autoimmune skin conditions (e.g., lupus)
❌ Pregnant or breastfeeding women
If immediate volumisation is needed, HA fillers may be a better alternative.
PDLLA-HA skin boosters e.g Juvelook is delivered using three different techniques depending on the treatment goals:
The treatment protocol varies depending on your age and skin concerns:
For Skin Texture and Radiance (30s and above): We may use PDLLA-HA skin boosters (e.g juvelook) with an injector gun for minimal downtime and discomfort.
✔️ Injector Gun allows even distribution of the product with minimal discomfort, minimising complications in the process
For Volumisation and Tightening (40s and above): More concentrated PDLLA- HA e.g Juvelook Volume or Lenisna may be injected subcutaneously using a cannula for uniform distribution.
✔️ Cannula Injection is used for skin tightening, volume restoration, and scar remodelling.
For Scar Remodeling: A combination approach is often used, with PDLLA-HA skin boosters injected directly into the skin or via cannula.
✔️ Direct Injection into scars is effective for atrophic acne scars and deep tissue remodelling.
✔️ Mild swelling and redness are common and resolve within 24-48 hours
✔️ Avoid sun exposure & excessive heat for the first 3 days
✔️ Regular skincare enhances treatment results
Most patients require 2-4 sessions of PDLLA-HA skin boosters e.g Juvelook,, spaced 4-8 weeks apart, to maximise collagen production and achieve optimal results.
When considering PDLLA-HA skin boosters e.g Juvelook Skin Booster as part of your anti-ageing and skin rejuvenation routine, one of the most common questions is, "How much does PDLLA-HA skin boosters cost in Singapore?" The price of this advanced hybrid HA-PDLLA treatment varies based on multiple factors, including the type of PDLLA-HA (Juvelook) product used, the number of sessions needed, and the expertise of the injector. For a quote, you can refer to the Lumine Dermatology price list or book a consultation.
Below, we’ll break down these cost factors so you can make an informed decision before undergoing treatment.
The cost of Juvelook Skin Booster in Singapore is not fixed and depends on several key elements, which influence the total price of treatment.
Not all PDLLA-HA treatments are the same. They are designed for different skin concerns, and their costs vary accordingly.
Because the higher concentration of PDLLA-HA (e.g Juvelook Volume or Lenisna) requires a more specialised injection technique and contains a higher concentration of PDLLA, its cost is higher than standard PDLLA-HA (e.g Juvelook) treatments.
Unlike traditional hyaluronic acid fillers, which provide instant volume, PDLLA-HA works by gradually stimulating collagen production. This means that multiple sessions are often required to achieve the best results.
The method of administering PDLLA-HA boosters e.g Juvelook play a role in its cost. Different injection techniques require different levels of skill and precision, and the experience of the medical practitioner will influence pricing.
Since PDLLA-HA treatments require precision and a customised approach, it is essential to visit a licensed clinic with experienced professionals who understand how to maximise its benefits while minimising risks.
PDLLA-HA hybrid skin booster e.g Juvelook is an advanced collagen-stimulating injectable, and choosing the right clinic is crucial for ensuring safe, effective, and long-lasting results. At Lumine Dermatology & Laser Clinic, we specialise in tailored skin rejuvenation treatments using the latest techniques to maximise Juvelook’s collagen-stimulating benefits.
✅ For Skin Hydration & Rejuvenation – If you want to improve fine lines, dullness, and overall skin texture, learn more about PDLLA-HA (e.g Juvelook Skin Booster).
✅ For Skin Tightening & Volume Loss – If you are looking for mild lifting and collagen banking, read about concentrated PDLLA-HA treatments e.g Juvelook Volume (Lenisna) for long-term skin firmness.
✅ For Acne Scars & Scar Remodeling – If you have atrophic acne scars or need skin resurfacing, find out more about our Scar Treatments to see how PDLLA- HA treatments can be combined with subcision, laser therapy, or microneedling RF for enhanced results.
Our team of specialists at Lumine Dermatology ensures that your PDLLA-HA treatment is customised to your unique skin needs.
At Lumine Dermatology & Laser Clinic, we are committed to providing safe, effective, and scientifically backed aesthetic treatments tailored to your unique skin needs.
✔️ Certified Medical Experts – Our team consists of a dermatology specialist who can perform skin rejuvenation and anti-ageing treatments.
✔️ Custom Treatment Plans – Every PDLLA-HA treatment is personalised based on your skin condition and goals.
✔️ State-of-the-Art Equipment – We utilise advanced injector technology and minimally invasive techniques for precision and maximum comfort.
✔️ Long-Term Skin Health Approach – We focus on gradual, natural enhancements rather than instant but short-lived results.
We use the latest techniques and technologies to ensure you achieve your desired outcomes safely and effectively.
If you’re considering PDLLA-HA treatment e.g Juvelook we invite you to learn more about our scar treatment services or explore our range of laser treatments to complement your results. For those interested in advanced skin tightening, discover how microneedling radiofrequency can enhance your results.
Ready to transform your skin with PDLLA-HA treatment e.g Juvelook? Book a consultation with us today and take the first step toward radiant, youthful skin. For detailed pricing, check out our price list for PDLLA-HA e.g Juvelook treatments.
By choosing PDLLA-HA treatments, you’re investing in a treatment that not only enhances your skin’s appearance but also promotes long-term skin health. Let us help you achieve the glowing, youthful complexion you deserve!
| Feature | Juvelook | Lenisna (Juvelook Volume) | Sculptra (PLLA-based) |
| Composition | 42.5mg PDLLA + 7.5mg HA | 170mg PDLLA + 30mg HA | 150mg PLLA |
| Purpose | Hydration + Collagen Stimulation | Skin Tightening + Collagen | Deep Tissue Volumisation |
| Longevity | Up to 2 years | Up to 2 years | Up to 2 years |
| Delivery Method | Needle, Injector Gun, Cannula | Needle, Cannula | Laser-assisted, Cannula |
| Depth | Dermal | Deep Dermal/Subcutaneous | Deep Dermal/Subcutaneous |
PDLLA-HA treatments provides a gentler approach to collagen banking, making it a preferred choice for individuals who want rejuvenation without excessive volume.
Yes, PDLLA- HA treatment is a safe and clinically tested treatment. It is HSA-approved in Singapore, meeting stringent safety and efficacy standards. Additionally, PDLLA is a biocompatible material, which means it gradually degrades into natural compounds (lactic acid, CO₂, and water) without causing harm to the body.
As with all injectable treatments, PDLLA-HA should be administered by a trained medical professional to ensure optimal results and minimise risks.
While PDLLA-HA treatment is generally well tolerated, some patients may experience mild, temporary side effects at the injection sites, including:
✔️ Mild swelling or redness – Usually subsides within 24–48 hours
✔️ Bruising – Minimal and resolves in a few days
✔️ Tenderness or slight discomfort – Generally mild and temporary
💡 Rare but potential risks:
If the product is not evenly distributed or is injected into high-movement areas (e.g., around the mouth), there is a slight risk of nodule formation. However, this can be prevented by choosing an experienced injector and following post-treatment care instructions.
Unlike hyaluronic acid fillers, which provide instant but temporary results, PDLLA-HA e.g Juvelook stimulates collagen production gradually for long-term skin improvement.
⏳ PDLLA-HA results typically last up to 2 years, depending on:
✔️ Age and metabolism – Younger individuals may maintain results longer because of higher collagen production rates.
✔️ Lifestyle habits – Smoking, excessive sun exposure, and poor skincare can accelerate collagen breakdown.
✔️ Number of sessions completed – Patients who undergo the full recommended treatment cycle see longer-lasting benefits.
Most individuals choose to maintain their results with yearly touch-ups to ensure consistent skin quality and firmness.
Yes. Juvelook pairs exceptionally well with other skin-enhancing treatments to maximise its effects. Combining treatments can address multiple concerns simultaneously, leading to more comprehensive and long-lasting improvements.
💠 For skin tone & radiance: Picosure Pro & MOXI Lasers – Helps even out skin tone, minimise pigmentation, and enhance radiance.
💠 For skin tightening & lifting: HIFU (High-Intensity Focused Ultrasound) – Improves facial contours and firms up loose skin.
💠 For acne scars & skin texture: RF Microneedling (Sylfirm X) – Works in combination with Juvelook to treat acne scars and refine skin texture.
💠 For collagen stimulation & deep hydration: Hyaluronic Acid Skin Boosters – Enhances hydration while Juvelook focuses on long-term collagen remodeling.
Combination treatments accelerate skin renewal and deliver superior anti-ageing benefits.
PDLLA-HA Treatment e.g Juvelook provides both immediate and long-term improvements.
✅ Immediate:
After the first session, skin hydration and plumpness are noticeable due to the hyaluronic acid (HA) component.
✅ Gradual:
Collagen stimulation begins within 3-4 weeks and continues to improve over the next 3-6 months.
✅ Long-Term:
The biostimulatory effects of PDLLA continue for up to 24 months, offering natural and long-lasting skin rejuvenation.
For best results, a full treatment cycle of 2-4 sessions is recommended, spaced 4-8 weeks apart.
While PDLLA-HA treatment e.g Juvelook is a versatile and effective skin booster, some individuals may not be suitable for treatment. It is not recommended for:
❌ Individuals with active skin infections or inflammation (e.g., severe acne, eczema, rosacea)
❌ Patients with autoimmune diseases affecting the skin (e.g., lupus, scleroderma)
❌ Pregnant or breastfeeding women
❌ Individuals looking for instant volume restoration (HA fillers are a better option in these cases)
During your consultation at Lumine Dermatology & Laser Clinic, our doctor will assess your skin condition and determine if PDLLA-HA treatment e.g Juvelook is the right choice for you.
To ensure optimal results and minimise potential side effects, follow these pre-treatment guidelines:
✔️ Avoid blood-thinning medications (e.g., aspirin, ibuprofen, fish oil) at least 3-5 days before treatment to reduce bruising.
✔️ Refrain from alcohol and smoking for at least 24 hours before the procedure to prevent delayed healing.
✔️ Stay well-hydrated and follow a healthy skincare routine leading up to your session.
✔️ If you have a history of cold sores, inform your doctor so they can prescribe preventative medication before treatment.
If you are looking for a long-term, non-invasive solution to improve skin hydration, texture, firmness, and collagen levels, PDLLA-HA treatment is a suitable skin booster. Unlike traditional HA fillers, which provide temporary volumisation, PDLLA-HA treatments stimulate natural collagen production, ensuring sustained skin improvements for up to 2 years.
Why Choose PDLLA-HA treatment?
✅ Stimulates natural collagen production for long-lasting results
✅ Hydrates, tightens and rejuvenates the skin without excessive volumisation
✅ Treats fine lines, wrinkles, pores, and acne scars effectively
✅ Minimal downtime, suitable for all skin types
✅ Safe and clinically approved in Singapore
Don’t wait to achieve youthful, glowing skin!
Visit our clinic for a consultation and take the first step toward collagen-stimulated, long-lasting skin rejuvenation! Contact us today to book your appointment!
