Dermatologist In Singapore - Lumine Dermatology Clinic
1 Scotts Road #04-15/16 Shaw Centre Singapore 228208

Juvelook vs Profhilo: Which Is the Better for Your Skin?

Juvelook vs Profhilo

Have you ever looked in the mirror and wished for smoother, firmer, and more radiant skin? If so, you're not alone. Many people seek effective treatments to rejuvenate their skin, restore hydration, and maintain a youthful glow. With so many options available, it can be overwhelming to choose the right one. Two of the most talked-about injectable treatments today are Juvelook and Profhilo. Both promise impressive results, but which one is better suited for your skin concerns?

At Lumine Dermatology, we specialise in advanced, science-backed skincare solutions. We understand that every individual’s skin is unique, and choosing the best treatment requires expert guidance. In this article, we’ll break down the differences between Juvelook and Profhilo, their benefits, how they work, and which one might be the best fit for your skincare needs.

What Is Juvelook?

Juvelook Poly D-L-lactic Acid (PDLLA)

Juvelook is a cutting-edge skin rejuvenation treatment designed to stimulate collagen production, improve skin elasticity, and enhance skin texture. Unlike traditional dermal fillers that primarily add volume, Juvelook works by encouraging the skin to heal and regenerate from within. This makes it a powerful option for individuals looking for long-term improvements in skin health.

Key Ingredients and How It Works

Juvelook combines two powerful active ingredients:

  • Poly D-L-lactic Acid (PDLLA) – A collagen stimulator that promotes the natural production of collagen, gradually improving skin firmness and structure.
  • Hyaluronic Acid (HA) – Known for its deep hydration properties, HA instantly boosts moisture levels, leading to smoother and plumper skin.

Once injected, Juvelook works at a cellular level by activating fibroblasts—cells responsible for collagen production. Over time, this leads to increased skin thickness, reduced fine lines, and improved overall skin quality.

Benefits of Juvelook for Skin Rejuvenation

  • Long-lasting collagen production – Unlike temporary fillers, Juvelook provides sustained improvements in skin texture and elasticity.
  • Targets multiple skin concerns – Effective in treating fine lines, acne scars, uneven skin tone, and mild skin laxity.
  • Natural-looking results – Rather than artificially plumping the skin, Juvelook enhances your natural features by strengthening the skin’s structure.
  • Minimal downtime – Mild redness or swelling at the injection sites may occur but typically resolves within 24–48 hours.

Ideal Candidates for Juvelook

Juvelook is a great option for individuals who:

  • Want to improve fine lines, wrinkles, and acne scars without adding volume.
  • Are looking for a treatment that stimulates natural collagen production for long-term results.
  • Have mild skin laxity and desire firmer, more youthful skin.
  • Prefer a non-surgical, minimally invasive aesthetic treatment.

However, those with active infections, autoimmune disorders, or who are pregnant should consult with a professional before undergoing Juvelook treatment.

What Is Profhilo?

Profhilo Hyaluronic Acid (H-HA)

Profhilo is an innovative injectable skin treatment designed to deliver intense hydration and stimulate collagen and elastin production. Unlike Juvelook which stimulates collagen by activating fibroblasts (collagen-producing cells) by low grade inflammation, Profhilo works as a bio-remodelling agent, restructuring the skin’s integrity by stimulating collagen, elastin and even fat cells (adipocytes) production. Profhilo may also have a slight visual lifting effect due to the high concentration of high molecular weight and low molecular weight hyaluronic acid injected into the skin, which increases skin turgor.

Unique Features and Mechanism of Action

Profhilo contains a very high concentration of pure Hyaluronic Acid (HA), which spreads evenly under the skin, delivering moisture and stimulating natural skin renewal through collagen and elastin production. The treatment is administered using the 5-Point Bio-Aesthetic Point (BAP) technique, ensuring even distribution and optimal results. Profhilo can also be injected by cannula to the under eye and forehead areas, as these areas are typically not treated in the traditional 5 point BAP technique.

Benefits of Profhilo for Skin Hydration and Firmness

  • Intense hydration – Profhilo deeply nourishes the skin, improving moisture levels and enhancing skin glow.
  • Stimulates elastin and collagen production – Leads to firmer, tighter, and more youthful-looking skin.
  • Smooths fine lines and wrinkles – Provides a natural lifting effect without excessive volume.
  • Minimal injections, maximum effect – The BAP technique requires only a few strategically placed injections for full-face treatment.
  • Natural results- as Profhilo is a bioremodelling treatment, the results are natural. This is important to patients who might not be keen on hyaluronic acid or collagen stimulating fillers.

Who Should Consider Profhilo?

Profhilo is best suited for individuals who:

  • Experience dry skin, dehydration, or loss of elasticity.
  • Want to improve skin texture, tone, and tightness.
  • Prefer a natural-looking, subtle enhancement rather than added volume.
  • Seek a quick and effective treatment with minimal discomfort.
  • Maintain healthy, supple skin to combat skin ageing

Juvelook vs Profhilo: Key Differences

Composition and Active Ingredients

  • Juvelook: This treatment combines PDLLA (Poly D-L-lactic Acid) and Hyaluronic Acid. PDLLA is a powerful collagen stimulator, working to restore the skin’s structural integrity over time. Meanwhile, Hyaluronic Acid provides immediate hydration, enhancing skin texture and plumpness.
  • Profhilo: Profhilo is composed of 100% pure Hyaluronic Acid in a high concentration. This allows for deep hydration and skin remodelling, making it a unique hybrid between traditional fillers and bio-remodelling injectables.

Treatment Process and Longevity of Results

  • Juvelook: Typically, 2–4 sessions are required, spaced 4–8 weeks apart. Since it works by stimulating collagen, the results gradually develop over 3–6 months and can last up to 24 months.
  • Profhilo: The treatment involves two sessions, spaced one month apart. Results appear much faster, often within a few weeks, but the effects last around 6–9 months before a maintenance session is needed.

Skin Concerns Addressed by Each Treatment

  • Juvelook: Best suited for individuals looking to address fine lines, wrinkles, acne scars, and mild skin laxity. Since it stimulates natural collagen production, it works well for those wanting gradual but long-lasting improvements.
  • Profhilo: Ideal for intense hydration, improving skin elasticity, and reducing early signs of ageing. It spreads evenly beneath the skin, delivering hydration to dry and ageing skin.

Injection Techniques

  • Juvelook: Administered microinjections or a cannula, depending on the area treated and desired results. Targeted injection sites ensure precise collagen stimulation.
  • Profhilo: Uses the 5-Point Bio-Aesthetic Point (BAP) technique, injecting small amounts of Hyaluronic Acid at strategic facial points for optimal absorption and distribution. Profhilo can also be injected via cannula to the forehead, temples and under-eye areas, which are areas that typically do not respond as well with the 5-Point BAP technique.

Downtime and Side Effects

  • Juvelook: Minimal downtime, with mild swelling and redness at injection sites that resolve within 24–48 hours. There may be mild bruising at the needle insertion points that can last up to 2 weeks.
  • Profhilo: Possible temporary bumps at the injection sites, which typically subside within a few hours to a few days. Bumps from Profhilo injected on the neck may take a longer time to subside. There may also be mild bruising at the needle insertion points that can sometimes last up to 2 weeks. 

Profhilo vs Juvelook: Which One Is Right for You?

Which One Is Right for You

Deciding between Profhilo and Juvelook depends on your specific skin concerns and aesthetic goals. If you’re primarily looking to restore skin hydration, improve elasticity, effect slight lifting without resorting to filler injections, and achieve a dewy, youthful glow, then Profhilo is a fantastic option. Its high concentration of Hyaluronic Acid (HA) deeply nourishes the skin, smoothing out fine lines and improving overall skin tone. The unique bio-remodelling effect of Profhilo works exceptionally well for those experiencing skin laxity, dryness, or early signs of ageing.

On the other hand, if your main goal is to stimulate long-term collagen production and strengthen skin structure, Juvelook might be the better choice. Thanks to its Poly D-L-lactic Acid (PDLLA) content, Juvelook doesn’t just hydrate but also works on a deeper cellular level, encouraging your skin to generate new collagen over time. This makes it an excellent solution for fine lines, acne scars, and improving skin resilience in the long run.

Achieve Radiant Skin with Lumine Dermatology

At Lumine Dermatology, we specialise in advanced, personalised skincare solutions that bring out the best in your skin. Our team of expert dermatologists and aesthetic specialists carefully assesses your unique needs and recommends treatments that deliver optimal results. Whether you choose Juvelook, Profhilo, or a combination of both, we ensure that you receive safe, effective, and customised care.

Your skin deserves the best possible treatment—one that enhances its natural beauty and health. Schedule a consultation with us today and take the first step toward youthful, glowing skin!

Frequently Asked Questions

Is the Treatment Painful?

Both treatments involve injections, so some mild discomfort can be expected. However, a topical numbing cream is often applied before the procedure to minimise any pain. The injections themselves are quick, and most patients describe the sensation as a slight pinch or mild stinging. Any discomfort usually subsides immediately after treatment.

Can Juvelook and Profhilo Be Combined?

Yes! Many patients combine Juvelook and Profhilo to maximise their skin rejuvenation results. While Profhilo deeply hydrates the skin, Juvelook stimulates collagen production over time. A combination approach can provide both instant hydration and long-term firmness, offering the best of both worlds.

How Long Do Results Last for Juvelook vs Profhilo?

  • Juvelook: Results can last up to 24 months after a series of 2-4 treatments, thanks to its long-term collagen stimulation effects.
  • Profhilo: The benefits of Profhilo typically last 6–9 months after 2 treatments spaced 1 month apart, after which a maintenance session may be required to sustain hydration and firmness.

Are These Treatments Safe?

Yes, both Juvelook and Profhilo are clinically tested, FDA-approved treatments with excellent safety profiles. Since they use biocompatible ingredients, they are generally well-tolerated with minimal risk of severe side effects. However, they should always be administered by a licensed and experienced practitioner to ensure optimal safety and effectiveness.

Are There Any Major Side Effects of Juvelook and Profhilo?

Side effects are usually mild and temporary. Most patients experience redness, slight swelling, or small bumps at the injection sites. These typically resolve within 24–48 hours. Some people may also have minor bruising, but this fades within a few days. More serious complications are extremely rare when treatments are performed by qualified professionals.

Can Juvelook or Profhilo Help with Acne Scars?

Yes, Juvelook is particularly effective in treating atrophic acne scars, as its collagen-stimulating properties help repair and regenerate skin tissue. Profhilo, while mainly designed for deep hydration and elasticity, can contribute to skin healing when combined with other targeted treatments. Profhilo is generally not a typical treatment when done as monotherapy  for acne scars.

What Is the Best Age to Start Juvelook or Profhilo?

There is no fixed age requirement for Juvelook or Profhilo. These treatments are ideal for individuals in their late 20s to early 30s who want preventative skin rejuvenation, as well as those in their 40s, 50s, and beyond looking to address visible signs of ageing, fine lines, and skin laxity.ir 40s, 50s, and beyond looking to address visible signs of ageing, fine lines, and skin laxity.

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